Effects of adrenergic activation to the action potentials and ionic currents of cardiac cells

نویسندگان

  • Ferenc Ruzsnavszky
  • János Magyar
  • János Szöllősi
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effects of ionic parameters on behavior of a skeletal muscle fiber model

All living cells have a membrane which separates inside the cell from it's outside. There is a potential difference between inside and outside of the cell. This potential difference will change during an action potential. It is quite common to peruse action potentials of skeletal muscle fibers with the Hodgkin-Huxley model. Since Hodgkin and Huxley summarized some controlling currents like inwa...

متن کامل

Comparison of the effect of quasitrapezoidal and rectangular pulses on bio- electrical activity, calcium spike properties and afterhyperpolarization potentials of Fl cells of Helix aspersa using intracellular recording

  While the effect of changes of stimulus waveform (quasitrapezoidal and rectangular current pulses) on nerve activation is clear, but there is no evidence on the effect of quasitrapezoidal pulses on ionic currents of cellular membrane. In the present study, the effect of depolarizing quasi-trapezoidal current pulses, in comparison with that of depolarizing rectangular current pulses, on firing...

متن کامل

Changes in ionic currents and b-adrenergic receptor signaling in hypertrophied myocytes overexpressing Gaq

Mitarai, Sayaka, Thomas D. Reed, and Atsuko Yatani. Changes in ionic currents and b-adrenergic receptor signaling in hypertrophied myocytes overexpressing Gaq. Am J Physiol Heart Circ Physiol 279: H139–H148, 2000.—Transgenic overexpression of Gaq causes cardiac hypertrophy and depressed contractile responses to b-adrenergic receptor agonists. The electrophysiological basis of the altered myocar...

متن کامل

Mechanism of Action of the Thyroid Hormone on the Heart

SUMMARY  The foliowing cardiac effects may be at­tributed to thyroxin:  1-Thyroxin augments all anaerobic pro­cesses in the body includ::ng the heart, and decreases the glycogen content of the heart ( 1, 2, 5, 27). The resistance of the heart to anoxia is increased in hyperthyroidism ( 25). 2- Thyroxin influences the cardiac weight and prevents cardiac atrophy (3, 8, 10, 11, 19, 20, 21, 30...

متن کامل

Relaxin increases heart rate by modulating calcium current in cardiac pacemaker cells.

Relaxin (RLX), a reproductive hormone of the insulin family, increases heart rate in experimental animals. The cellular and ionic mechanisms responsible for this positive chronotropic effect remain unknown. We have investigated the actions of RLX on the action potential and underlying transmembrane ionic currents in single sinoatrial node cells of the rabbit heart under whole-cell voltage-clamp...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014